Global and Renal Oxygenation Assessment Tool

Inputs

Enter values
Anthropometrics (used for LBM, default kidney mass estimate)
Units:
Important: Non-Standard Renal Anatomy Considerations

For patients with single kidney (congenital or post-nephrectomy), horseshoe kidney, renal transplant, or marked asymmetry/atrophy, both:
  • Renal mass (affects estimated O₂ demand / VO₂), and
  • Renal blood flow distribution (affects effective O₂ delivery / DO₂)
may differ from standard assumptions. Consider available imaging, functional studies, and clinical context when interpreting results for anatomical variants.
In these scenarios, results are best treated as screening-level physiology, not precise organ quantification.
Kidney Measurements (CT / Ultrasound) (optional override)
Enter 3 dimensions per kidney
Right kidney L × W × D
Left kidney L × W × D
Tip: Kidney dimensions are expected in centimeters (cm). If values appear unusually large (e.g., entered in millimeters), they will be automatically converted. Decimal commas (e.g., 11,5) are also accepted.
Oxygen Content & Hemodynamics (current patient state)
NOTE: k is a modeling constant that links kidney mass to estimated renal VO₂. Leave blank to use the default (0.08).
"Effective Renal Fraction" represents usable renal oxygen-delivery fraction (not directly measured RBF). Baseline is set within the normal range (default 0.25). Modifiers (starting with CHF) reduce the effective fraction used in downstream calculations; baseline remains normal physiology.
Effective Renal Delivery Modifiers (affect effective renal fraction)
pick what applies
CHF / Cardiorenal physiology Targets common teaching ranges using baseline-normal physiology:
Cirrhosis / HRS physiology Caps effective renal delivery fraction (conservative tiers):
Warning: Vasopressors may raise blood pressure yet fail to improve, and may worsen renal medullary oxygenation while improving oxygenation of the renal cortex. Their net renal effects are highly context-dependent and therefore are not included in this calculation.
Renal Metabolic Efficiency Modifiers (affect VO₂/“efficiency coefficient”)
worst single modifier wins
AKI / tubular injury Increases inefficiency (coeff. later)
CKD (≥ stage 3) Increases inefficiency (coeff. later)
Sepsis physiology Potential mitochondrial dysfunction (coeff. later)

Outputs

Body & Kidney Metrics (derived)
baseline physiology

BMI kg/m²

(pending)

BSA (Mosteller)

(pending)

Lean body mass kg

(pending)

Kidney volume (total) mL

(pending)

Kidney mass (total) g

(pending)

Kidney mass source

(pending)

Total blood volume (Nadler) L

(pending)

Hemoglobin mass g

(pending)

Global DO₂ Index (DO₂i) mL/min/m²

(pending)
Significant global oxygen delivery deficit detected.
Systemic DO₂ index of XX mL/min/m² is below published safety thresholds associated with a significantly increased risk of AKI, even before renal-specific modeling.
Critical global oxygen delivery deficit detected.
Systemic DO₂ index of XX mL/min/m². DO₂i values below YY mL/min/m² are associated with a critical risk of organ dysfunction in published research literature, independent of renal-specific modeling.
Oxygen Content & Delivery (systemic → renal)
CaO₂, DO₂

CaO₂
(Oxygen Content) mL O₂/dL

(pending)

Total O₂ carrying
capacity (systemic) mL O₂/min

(pending)

Renal Blood Flow L/min

(pending)

DO₂ (renal, effective) mL O₂/min

(pending)
Consumption, Stress, and Targets (VO₂, OER, Hb solver)
core logic

VO₂ (renal estimate) mL O₂/min

(pending)

VO₂ coefficient mL/min/g

(default 0.08)

Renal metabolic efficiency (applied) unitless

(pending)

OER
(Raw) %

(pending)

OER (Augmented) %

(pending)

Required OER (target) %

15% (default target)

Minimum Hemoglobin
to reach OER of 15% g/dL

(pending)

Hemoglobin deficit
(kidney-related) g/dL

(pending)
Inner Medulla Guidance (primary vulnerability target)
Derived from renal OER (slope model). IM baseline OER target 85% or less.

Inner Medulla OER
(derived, capped at 100%) %

(pending)

Inner Medulla OER
stress threshold %

85.0

Inner Medulla status
(current)

(pending)

Hb needed to reach
Renal OER of 15% g/dL

(pending)

Guidance

(pending)

Global DO₂i if Hb corrected to renal OER target of 15% mL/min/m²

(pending)
This IM section is derived from the renal augmented OER using a conservative slope model anchored at: renal OER 15% → IM OER 85% (baseline target) and renal OER 35% → IM OER 100% (failure point). IM OER is shown uncapped for research purposes.